What are the standad test when you want to check protein function? - Ask Science Questions most recent 30 from http://asksci.com 2010-07-29T19:24:36Z http://asksci.com/feeds/question/104 http://www.creativecommons.org/licenses/by-nc/2.5/rdf http://asksci.com/questions/104/what-are-the-standad-test-when-you-want-to-check-protein-function What are the standad test when you want to check protein function? Aya 2009-11-05T18:00:53Z 2010-07-18T22:11:18Z <p>I did some test to find out the function of a protein group. I would like to know of there are standard Test I can do, maybe something with a wider range of possibilities then what I am doing now.</p> http://asksci.com/questions/104/what-are-the-standad-test-when-you-want-to-check-protein-function/105#105 Answer by glucose for What are the standad test when you want to check protein function? glucose 2009-11-08T02:38:12Z 2009-11-08T02:38:12Z <p>Should you first check the sub cellular localization?</p> http://asksci.com/questions/104/what-are-the-standad-test-when-you-want-to-check-protein-function/297#297 Answer by derfritz for What are the standad test when you want to check protein function? derfritz 2010-07-18T22:11:18Z 2010-07-18T22:11:18Z <ol> <li>Check the sequence in databases to get some ideas. Soluble or membrane? Any localisation signal?</li> <li>Overexpress maybe as GFP-Fusionprotein and test your theory from (1)</li> <li>Downregulate by RNAi and test your theory from (1) and (2)</li> <li>Pull-down assay and check associated proteins</li> </ol>